Bradley Roby and Lorenzo Doss better have another big game up their sleeve, because Aqib Talib has officially been ruled out of Sunday night’s matchup against the Oakland Raiders.

While Talib may be the best cornerback in the NFL this season, Roby and Doss did a heck of a job filling in last week. Roby earned AFC Defensive Player of the Week honors and Doss was Pro Football Focus’ highest-graded cornerback of Week 8.

The Oakland Raiders are a different beast, though.

Derek Carr is playing at a near-MVP level, and the combo of Amari Cooper and Michael Crabtree just might be the best receiving duo in the NFL.

The “No Fly Zone” will have their hands full in primetime.